Applications of Microfat and Nanofat in Urology & Gynecology
Solutions for Urology & Gynecology
The benefits of microfat and nanofat are becoming more widely recognized in urology and gynecology treatments worldwide.
These advanced techniques involve:
1. Harvesting small amounts of the patient’s own adipose tissue or Adipose Tissue Complex (ATC) and standardizing the injectability of the tissue. This is microfat and is a natural filler and volumizer.
2. Sizing the microfat down to Tissue Stromal Vascular Fraction (tSVF) or nanofat. Nanofat is regenerative in nature (not volumizing) and can be injected intradermally with a needle as small as 30g.
Tulip Medical is invested in supporting international research on the expanding benefits of using microfat and nanofat in non-surgical applications that can improve the way we treat patients with these difficult, quality-of-life-affecting conditions.
In urology, these advanced fat grafts are being used for conditions such as stress urinary incontinence, erectile dysfunction, Peyronie’s disease, and anal fistula. Microfat and nanofat injections may aid in tissue repair and regeneration, potentially improving pelvic floor support for urinary incontinence and enhancing vascularization in the case of erectile dysfunction, Peyronie’s disease, and anal fistula.
In gynecology, these fat grafts find applications in addressing issues like vaginal laxity, dryness and scarring. Nanofat injections, in particular, hold promise for improving tissue quality, promoting collagen synthesis, and addressing the effects of aging, menopause, or trauma.
The regenerative potential of microfat and nanofat presents a minimally invasive approach to addressing various urological and gynecological concerns that are otherwise very difficult to treat, offering new avenues for enhancing patient outcomes and quality of life. Ongoing research in these fields is growing and supports the efficacy and expanding applications of microfat and nanofat in urological and gynecological contexts.
“We treat Urethro-vaginal fistulae patients with microfat and nanofat to regenerate and to fill the layers of the reconstruction and the results are very good”
Elisa Berdondini, MD | Urologist
Urological and Gynecological Uses for Microfat and Nanofat
Microfat and nanofat obtained with the Tulip Nano System can be used in a wide variety of surgical and office-based procedures:
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Promote Tissue Renewal for
Vaginal Rejuvenation -
Increase Vaginal
Lubrication and Sensitivity -
Induce Healing of
Perineal Scarring and Trauma -
Regenerate the
Dermis for Rejuvenation -
Restore Volume to Aging
Vulvas and Labia Majora -
Urethral and
Genital Lichen Sclerosus -
Peyronie’s Disease
-
Urinary Incontinence
-
Erectile Dysfunction
-
Urethral Stricture
-
Urethral Diverticula
Understanding the Difference Between Microfat and Nanofat
Microfat and nanofat are adipose fat tissues that maintain the regenerative properties of native fat. Microfat can often be delivered through needles or cannulas that range from 18g to as small as 25g in diameter, depending on the fibrosity of the patient’s fat. Microfat is injected subdermally and adds volume and structure to the recipient site.
Nanofat’s primary benefit is regeneration. Nanofat consists of a regenerative matrix, which is key to tissue repair and skin rejuvenation. It is usually injected intradermally but can also be applied topically. True Nanofat™, obtained with the Tulip system, is validated to be injectable with needles as small as 30g.
Together, microfat and nanofat have a wide potential to treat your patients without the need for invasive surgical procedures. They can also work in tandem with traditional surgical intervention to promote wound healing and scar mitigation.
Urological and Gynecological Us
Robert Alexander, MD, DMD, FICS
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Incorporating Regenerative Microfat and Nanofat into Your Practice
Whether you use microfat and nanofat in a standalone procedure or in conjunction with surgery, Tulip’s patented technology makes your experience with microfat and nanofat safe, easy, predictable, and cost-effective. As the leading company in fat transfer for over 30 years, Tulip has the expertise to help you incorporate the use of orthobiologics into your practice.
Everything You Need to Obtain Microfat and Nanofat: The Tulip GOLD Kit
Tulip’s GOLD (Gentle Office-Based Lipoaspirate Delivery) kit provides everything you need to harvest and prepare microfat and nanofat for use in an office-based or surgical setting.
Using a closed syringe lipoaspiration system, our GOLD kits provide a less traumatic and more efficient approach to acquiring Adipose Tissue Complex (ATC) as a structural graft without surgery.
- The protocol and the kit have been clinically validated for safety, ease of use, viability, and consistent output, leading to more predictable outcomes.
- Tulip’s “Soft Harvest System” provides a safe and efficacious low-pressure acquisition of ATC.
- The harvested fat can be used as microfat (which is not sized down) or sized down into nanofat.
Tulip GOLD Kits Provide These Advantages for Urological and Gynecological Medicine
- Safe and easy-to-use closed adipose tissue harvesting and sizing
- Validated process resulting in consistently high concentrations of regenerative ATC and nanofat that is validated to be injectable with needles as small as 30g
- Increased patient safety by using their own tissue
- Set your practice apart by offering the minimally invasive, regenerative treatments patients are asking for
Curating Science
Published articles on the science behind adipose regenerative therapies and the varied functional uses of adipose in urology and gynecology.
- One-stage anterior urethroplasty with nanofat grafting: Preliminary results in our referral center
- Novel technique of vulvo-vaginal rejuvenation by lipofilling and injection of combined platelet-rich-plasma and hyaluronic acid: a case-report
- Lipofilling of Perineal and Vaginal Scars: A New Method for Improvement of Pain after Episiotomy and Perineal Laceration
- Nanofat Cell Aggregates: A Nearly Constitutive Stromal Cell Inoculum for Regenerative Site-Specific Therapies
- Application of nanofat for treatment of traumatic faecal incontinence after sphincteroplasty – A pilot study
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